The RDA Multi-Omics Metadata Standards WG is a multidisciplinary working group is comprised of a variety of subject matter experts and research support professionals across Omics technology domains in areas of Genomics, Proteomics, Metabolomics, and Lipidomics. Multi-omics data integration involves merging different Omics data types and metadata capture methods using high-throughput technologies for quantification and characterization of large complex pools of biological molecules. A unrelenting challenge Multi-omics data integration often faces is the vast array of fragmented data types and data standards (metadata reporting guidelines, terminologies/ontologies, models/formats, and identifiers schemas) generated across the different Omics domains, making it difficult to manage and reuse prior to integration. This working group aims to provide clear recommendations and supporting deliverables based on careful curation and dissemination of evaluated Multi-omics community standards across domains that serve to support flexible harmonization of Multi-omics data and metadata standard integrations. Thus far, our working group has actively collected and curated >220 existing Omics domain data standards leveraging existing Omics records at FAIRsharing (in collaboration with the FAIRsharing WG) and additional domain affiliated resources in filling existing Multi-omics standard curation gaps with included data lifecycle application coverage. Based on our initial landscape review we have begun defining our selection criteria for down-selecting curated standards, both subject agnostic and domain-specific, for inclusion in our FAIRsharing Multi-Omics Standards Collection as a machine-actionable approach in creating an open community-driven Multi-Omics standards recommendation resource supporting future data management and sharing approaches.

We anticipate the completion of our first set of deliverables (prior to VP23) outlined in our case statement, which includes a Landscape Review of existing Omics community standards (Deliverable 1a) and Multi-omics Standards Collection located at FAIRsharing (Deliverables 1b) as a result of our defined selection criteria activities. This session will serve to collect any relevant feedback or proposed revisions community stakeholders may have on our first set of deliverables, including all supplementary training materials supporting WG Multi-omics standard record criteria selections aggregated under our FAIRsharing Multi-Omics Collection. Following VP23, our WG will begin planning work for our next deliverable (crosswalk analysis of selected standard records aggregated under Deliverable 1b for identifying metadata reporting integration gaps and cross-domain standard element adoption opportunities).

WG Case Statement: https://www.rd-alliance.org/rationale/rda-ofr-creating-a-multi-omics-metadata-schema-standard-reporting-matrix-wg/|Multi-omics Landscape Review (Deliverable 1a) : https://docs.google.com/spreadsheets/d/16FcvFbDjb1lBL71o0Lvf5mLk0MQ1Otspghwm4twfQ7I|WG VP22 Slides: https://doi.org/10.5281/zenodo.11552128|FAIRsharing Educational Material:

The RDA Creating a Multi-omics Metadata Schema Standard Reporting Matrix WG was recognized and endorsed in December 2023. This WG has been very productive in the first 6 months following RDA endorsement and have begun producing our first set of deliverables for upcoming review. There is still great opportunity for new members to contribute their ideas and initiatives as we move forward in developing our next set of working deliverables. This WG is in active development and will produce a series of deliverables, as outlined in our case statement, by scope and sequence for subsequent recommendation as we progress.